Richard Lehman’s journal review—16 September 2013

NEJM  29 Aug-12 Sep 2013  Vol 369 799   When comparing a new fixed-dose anticoagulant with conventional warfarin based anticoagulation, what do you look for? Thrombotic events, death, major bleeding? Yes, certainly. But what makes the comparison meaningful? That depends largely on how well the warfarin group were kept within the target INR range. In the […]

Read More…

William Cayley: Does uncertainty and fear of the unknown drive overdiagnosis?

Edward Davies hits the nail on the head: “The fear of both patient and doctor can sometimes override the best knowledge, research, and information known to man.” I do not think, however, that it is just fear of getting sued that drives us physicians towards over-testing and overdiagnosis. Rather, it is existential fear of uncertainty, […]

Read More…

Leana Wen: Where to begin the conversation on overdiagnosis

One of the many takeaways from this week’s excellent Preventing Overdiagnosis Conference is that it’s hard for doctors to tell their patients that too much care is bad. For so long, the rhetoric has been about the danger of too little care. Newspapers brim with stories of death from missed diagnosis and lack of access […]

Read More…

David Payne: Open House London’s healthy buildings

Akerman—a £12.3m community healthcare building designed by the architectual practice Henley Halebrown Rorrison—opened last year as part of the regeneration of Myatts Field North in the south London borough of Lambeth. Sandwiched between homes and a local park, the bold white building stretches for 80m and, according to its architects, was designed to mimic the flat […]

Read More…

William Cayley: Measurement—at the expense of success

“Doc, how’s my blood pressure? What about my cholesterol? How about my weight?” “There’s room for improvement,” I say. “How much do you exercise? How many fruits and vegetables do you eat?” “Oh, I’m too busy right now for exercise—and I have to eat what I can get when I’m on the road. But I […]

Read More…

Edward Davies: Overdiagnosis—what are we so afraid of?

Evidence based medicine is first and foremost at the Preventing Overdiagnosis Conference in Dartmouth this week. The importance of data, research, and careful analysis has been repeatedly hammered home, with talks catchily entitled such as, “Does inclusion of  total cholesterol in mortality risk algorithims lead to overestimation of risk?” “Ten years prospective data from the […]

Read More…

Liu Xu et al: Chinese doctors leaving public hospitals—brain drain or emancipation?

      Recently the resignation of Yu Ying, a Chinese female doctor from a famous public hospital has provoked heated discussions among the Chinese netizens. Yu Ying was an emergency care physician at the Peking Union Medical College Hospital before her resignation. She has a Weibo, the Chinese equivalent of Twitter, with the name, […]

Read More…

Tessa Richards: Lifting the lid on information and learning from it

Progress. The march towards giving patients online access to their medical records is accelerating. The Society of Participatory Medicine has put out the bunting in welcome to the announcement by the OpenNotes initiative that 1.8 million more US patients can see and share full versions of their doctor’s notes; and that big US providers, including […]

Read More…

Richard Smith: Is the pharmaceutical industry like the mafia?

The piece that follows is my foreword to a new and fascinating book by Peter  Gøtzsche, the head of the Nordic Cochrane Centre, entitled Deadly Medicines and Organised Crime: How Big Pharma Has Corrupted Healthcare. I hope that this piece might prompt you to read the book. I was not paid for my foreword and […]

Read More…