A gap in the evidence—what is the role of surgery in the patient with severe (secondary) Raynaud’s phenomenon?

This blog is part of a series of blogs linked with BMJ Clinical Evidence, a database of systematic overviews of the best available evidence on the effectiveness of commonly used interventions. By Ariane Herrick and Lindsay Muir People with Raynaud’s phenomenon secondary to an underlying disease or condition (the best researched one being systemic sclerosis) […]

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Joanna M Zakrzewska and Mark E Linskey: Trigeminal neuralgia—gaps in the evidence

This blog is part of a series of blogs linked with BMJ Clinical Evidence, a database of systematic overviews of the best available evidence on the effectiveness of commonly used interventions. Trigeminal neuralgia is a rare condition that causes excruciating intermittent short-lasting, usually unilateral facial pain especially provoked by light touch. Although the criteria for […]

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Hans Lund: A brief introduction to the concept of evidence-based research

This blog is part of a series of blogs linked with BMJ Clinical Evidence, a database of systematic overviews of the best available evidence on the effectiveness of commonly used interventions. The scientific ideal On 15 February 1676, in a letter to his colleague (and rival) Robert Hooke, Sir Isaac Newton wrote the following well […]

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Huw Llewelyn: The way forward from “rubbish” to “real” EBM in the wake of Evidence Live 2015

This blog is part of a series of blogs linked with BMJ Clinical Evidence, a database of systematic overviews of the best available evidence on the effectiveness of commonly used interventions. At Evidence Live Iona Heath reminded us that EBM should not interfere with wisdom and common sense. Trish Greenhalgh gave a hilarious example of “rubbish […]

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Richard Saitz: An EBM challenge—What to do when clear cut evidence doesn’t exist

This blog is part of a series of blogs linked with BMJ Clinical Evidence, a database of systematic overviews of the best available evidence on the effectiveness of commonly used interventions. The case of so-called “moderate” drinking It is “bad” enough when we have randomized trials to guide practice. What I mean is, of course […]

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Gabriel Rada: How much health evidence is there in the world?

This blog is part of a series of blogs linked with BMJ Clinical Evidence, a database of systematic overviews of the best available evidence on the effectiveness of commonly used interventions. Thirty five years ago, Archie Cochrane reproached the medical profession for not having managed to organise a “critical summary, by specialty or subspecialty, adapted […]

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Paul Glasziou: Six proposals for evidence based medicine’s future

This blog is part of a series of blogs linked with BMJ Clinical Evidence, a database of systematic overviews of the best available evidence on the effectiveness of commonly used interventions. Gordon Guyatt coined the term “Evidence based medicine” (EBM) over 20 years ago, and it has had a remarkable global influence. But EBM is […]

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James McCormack and Mike Allan: Simply making evidence simple

This blog is part of a series of blogs linked with BMJ Clinical Evidence, a database of systematic overviews of the best available evidence on the effectiveness of commonly used interventions. In an ideal world in which shared decision making is practised with impunity, healthcare providers need—at their fingertips—an appreciation and understanding of (as well […]

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Victor Montori: Clinical evidence for the Brave New World of multimorbidity

This blog is part of a series of blogs linked with BMJ Clinical Evidence, a database of systematic overviews of the best available evidence on the effectiveness of commonly used interventions. The most common chronic condition worldwide is, or will soon be, multimorbidity. While it was previously a concern reserved for the very old, multimorbidity […]

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