Richard Lehman’s journal review – 30 August 2011

JAMA  24-31 Aug 2011  Vol 306 840   Every GP knows that some patients who are admitted to hospital come out without their usual medication and take this as an indication that they don’t need it any more. This happens particularly after admission to ICU. The team doing this cohort study in Ontario makes an attempt […]

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Richard Lehman’s journal review – 8 August 2011

JAMA  3 Aug 2011  Vol 306 493    This issue of JAMA is devoted to war and violence, things that most of us have not experienced. Those who do experience them, like most of the population of Europe in the generation before mine, are never unscathed. The study here discovers that military veterans with post-traumatic stress […]

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Philip Wilson: The dangers of science by press release

Imagine you’ve just completed a groundbreaking piece of research. Do you: a) go and tell your mates down the pub; b) publish in a peer reviewed journal; or c) rush out a press release? According to legend, Crick and Watson stylishly chose “a” after they discovered the structure of DNA, strolling into The Eagle in […]

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Gary Collins: Opening up multivariable prediction models

Consensus-based guidelines for transparent reporting Prediction models can provide reliable estimates of a patient’s risk (or probability) of having a specific underlying condition or of developing some condition in the future. Prediction models have consistently outperformed estimates made by individual doctors. Familiar examples include the Framingham Risk Score for cardiovascular disease, the APACHE score for […]

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Domhnall MacAuley: Waste, uncertainty, post publication peer review and the unintended consequences of asking a question

Irrelevant, misdirected, inappropriate, or unnecessary. Reading the list of contents in some lesser known journals or abstracts at a conference, you wonder what some studies really add. Sir Iain Chalmers (The Lind Initiative), who opened the Society of Primary Care conference in Bristol, called it waste. He said that we need to focus on uncertainty […]

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Richard Lehman’s journal review – 18 July 2011

JAMA  13 July 2011  Vol 306 Unusually, I couldn’t find anything to report on from JAMA this week. Last week, its new editor, Howard Bauchner, promised us a new vision for the journal. I liked the old journal very much but it was becoming like an old jumper *– full of comfortable associations but saggy […]

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Domhnall MacAuley: Public health summer school

Does your research really matter? Most VIP introductions are bland and unchallenging. Not this time. When (Professor Sir) Peter Gregson, vice chancellor at Queen’s University Belfast, introduced the joint summer school of the UK Clinical Research Collaboration’s centres of public health and Health Research Board (Ireland), he pointed out how universities often fail to show the […]

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