Richard Lehman’s journal review—25 January 2016

NEJM 21 Jan 2016 Vol 374 Share data or be damned OL The most important article this week also appears on the websites of JAMA, The BMJ, Annals of Internal Medicine, and The Lancet. It’s a proposal from the International Committee of Medical Journal Editors to move towards a requirement that all published research should […]

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Kamal R Mahtani on utilising systematic reviews: Is another trial necessary or ethical?

You don’t have to look too far to see the benefits of systematic reviews and their summary results. The well known Cochrane logo depicts a real example, highlighting the value of systematically pooling data for meta-analysis and in this case demonstrating the clear benefit of corticosteroids in accelerating lung maturation in preterm babies. Systematic reviews […]

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Jeffrey Aronson: When I use a word . . . Fifty up

This is the fiftieth blog in my “When I Use a Word” series. You’ve been counting, of course. To appreciate fully the range of words that imply “five” and “fifth”, “fifteen” and “fifty” requires an understanding of the phonetic phenomenon of assimilation, which is the modification of a sound in a word, phrase, or sentence, […]

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Peter Doshi: Roche to publicly post trial protocols—just kidding

“Thirdly, we will post the protocol of our trials as they are started and the results of trials once they are completed on two websites which are available to the public, clinicaltrials.gov and roche-trials.com.” So states Roche in describing one element of its 2013 policy on clinical trial data sharing. Such a policy would place […]

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Ahmed Rashid on “Goldilocks Medicine”: the quest for “just right”

Week after week, NHS general practitioners receive messages about changes they should consider making to their clinical practice. These messages come from national and local guidelines, research papers, blogs, social media, and articles in the medical and lay press. It can often feel like these messages are pulling doctors in all sorts of different directions. […]

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Andrew Moscrop: Should we extend NHS charges for overseas visitors and migrants?

Jeremy Hunt has been talking “tough measures.” Not junior doctors’ contracts, but migrants. Overseas visitors and migrants who get sick in Britain should be charged for using A&E and primary care health services, the Health Secretary says. Until now, non-UK residents have only ever had to pay for non-urgent hospital care. Jeremy Hunt proposes that […]

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