Sean P David: A way forward from ENDS to the tobacco end game

Combusted tobacco cigarette use causes about six million deaths per year and has been projected to cause one billion deaths in the 21st century. [1] The risk of tobacco smoking is very high (50% risk of death before age 70). [2, 3] However, the risk of death from using electronic cigarettes (e-cigarettes)—or electronic nicotine delivery […]

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Simon Chapman: When will the tobacco industry apologise for its galactic harms?

Last week, four US tobacco companies finally reached agreement with the US Department of Justice to fund large scale corrective advertising about five areas of tobacco control. Each advertisement will include the statement that the companies “deliberately deceived the American public.” The case against the companies commenced in 1999 and saw a 2006 judgment by […]

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Richard Lehman’s journal review—20 January 2014

NEJM  16 Jan 2014  Vol 370 201    Developing and marketing a new drug is a tricky business, but it can be a very lucrative one. AiCuris is a company I hadn’t heard of before, but it seems to specialize in antiviral drugs. For such a company, herpes simplex 2 infection presents a huge market opportunity: […]

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Carolyn Thomas: Why physicians must stop saying: “we are all patients”

While noodling around on Linked In one day, I was pleased to notice that the professional networking site has some member groups discussing patient engagement. I’m a heart attack survivor, a blogger, and a women’s health activist—so I also consider myself a fairly engaged patient. Maybe I should drop in on one of these groups […]

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Richard Lehman’s journal review—13 January 2014

JAMA Internal Medicine  Jan 2014  Vol 174 I was amazed at the richness of the contents of JAMA Intern Med this week, but then I sadly realized that the journal has changed from being a fortnightly treat to being a monthly one. I had been warned this would happen; it’s a natural consequence of online […]

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William Cayley: Evidence based medicine—it’s time to be critical

“If it ain’t broke, don’t fix it” goes the aphorism—and so would say any who trust complacently in the exponential growth of “evidence based” this or that in medicine. Des Spence, for one, disagrees. In a recent BMJ editorial he argues evidence based medicine (EBM) is broken, it is “now the problem, fuelling overdiagnosis and […]

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Richard Lehman’s journal review—6 January 2014

NEJM  26 Dec 2013  Vol 369 2481   There was no let up in the American journals over what they call the holiday period, and the NEJM offered a trial of a new GSK influenza vaccine to our attention on Boxing Day. It is a quadrivalent vaccine containing inactivated influenza B virus of both main lineages, […]

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