The BMJ Today: Alcohol pledges, fake antibiotic fixes, and NFL payouts

• The UK government’s responsibility deal with the alcohol industry promises to remove a billion units of alcohol (about 2% of consumption) from the market, through reducing the strength of alcoholic drinks such as beer and wine. The interim report from the government has been published, and claims that the deal has already worked better than […]

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The BMJ Today: An ancient enemy, School-EduSalt, and “low value care”

TB. An ancient enemy getting stronger • BMJ is supporting the World Health Organization’s End TB strategy by highlighting World TB Day today and offering free access to TB papers and resources. In an editorial for The BMJ, Zarir F Udwadia et al write that TB is India’s silent epidemic and a death sentence for poor […]

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The BMJ Today: Regulator will hunt down apps that harm patients

Action to be taken against apps that harm patients A UK health regulator has issued a warning to makers of mobile medical apps that may harm patients. Speaking at a health technologies seminar in London on 18 March, Neil McGuire, clinical director of devices at the Medicines and Healthcare Products Regulatory Agency (MHRA) said, “Be under […]

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The BMJ Today: Statins in pregnancy, sexual health in Pakistan, and mammography screening

Statins in pregnancy Bateman and co-workers report a well designed epidemiological study on statins in early pregnancy. Their analysis did not find a significant teratogenic effect from maternal use of statins in the first trimester. In a related editorial, Françoise Haramburu and co-workers state that the new safety data are reassuring, but suspension of treatment […]

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The BMJ Today: Prescribing on sparse evidence, homeopathy, and research methodology

How to prescribe when the evidence is lacking • Several observational studies have shown associations between using drugs with anticholinergic side effects—such as loperamide, loratadine, baclofen, amitriptyline, oxybutynin, or chlorphenamine—and cognitive decline. Links have also been shown with earlier death, falls, and admission to hospital with confusion and dementia. “But is this cause, or is […]

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The BMJ Today: Treatments for inflammatory diseases

A combination of old drugs is not inferior to biologics for rheumatoid arthritis • Tumor necrosis factor inhibitors are safe and effective therapies for patients with rheumatoid arthritis resistant to methotrexate and other disease modifying drugs, but they are very expensive. The BMJ Today reports the results of an open label pragmatic trial—the TACIT trial—that […]

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BMJ Today: Reassurance on varenicline, caring (or not) for NHS staff, and more holiday for emergency doctors

Good news for quitters A research paper in The BMJ today “is the most comprehensive published review to date of the neuropsychiatric safety of varenicline.” It was necessary, say the authors from Bristol University, because while several studies have found no evidence of an increased risk of neuropsychiatric side effects with varenicline, these studies have […]

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