It seems to me that the two most important goals in treating type 2 diabetes are to preserve the remaining beta cells and to reduce cardiovascular risk. And it seems to me that the main message of the UKPDS trial is that HbA1c is a useless surrogate marker for either of these. […]
John Morris’s magisterial history, The Age of Arthur, is full of astonishing insights into the transition between Roman Britain and Anglo-Saxon England, none more so than his description of the role played by the great plague of Justinian in the middle of the sixth century. […]
The treatment of “heart failure […]
“Even after careful clinical and mammographic evaluation, cancer is found in the contralateral breast in up to 10% of women who have received treatment for unilateral breast cancer. […]
Coming a day before April 1st, I couldn’t decide whether this paper, “Towards sustainable clinical trials […]
In a week that has seen several failed trials of cholesterol-tinkering, it’s good to see a successful trial of an agent which reduces major coronary events in hypercholesterolaemic patients without changing their cholesterol levels. […]
We dole them out, but 20-50% of the pills we prescribe remain on the shelf. […]
This has not been a good season for magnolias in Great Britain: […]
Reduction of Atherothrombosis for Continued Health (REACH) could be a description of what we spend half our time doing in primary care, but it is also the name of a big 44-country register of people with known atherosclerosis or with 3 or more risk factors. […]
In England they used to be known as firemen, even when this invited confusion with the stokers of steam locomotives, but now they are usually called by the more heroic name of firefighter, after the American practice. […]