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From will to live to will to die: oncologists, nurses, and social workers identification of suicidality in cancer patients. Granek L, Nakash O, Ariad S, Chen W, Birenstock-Cohen S, Shapira S, Ben-David M Support Care Cancer. 2017 Dec;25(12):3691-3702 A qualitative study in Israel, interviewed 20 nurses, 23 oncologists and 18 social workers and used grounded […]

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Effect of an Indwelling Pleural Catheter vs Talc Pleurodesis on Hospitalization Days in Patients With Malignant Pleural Effusion: The AMPLE Randomized Clinical Trial. Thomas R, Fysh ETH, Smith NA, Lee P, Kwan BCH, Yap E, Horwood FC, Piccolo F, Lam DCL, Garske LA, Shrestha R, Kosky C, Read CA, Murray K, Lee YCG. JAMA. 2017 […]

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Respiratory adverse effects of opioids for breathlessness: a systematic review and meta-analysis. Verberkt CA, van den Beuken-van Everdingen MHJ, Schols JMGA, Datla S, Dirksen CD, Johnson MJ, van Kuijk SMJ, Wouters EFM, Janssen DJA Eur Respir J. 2017 Nov 22;50(5). The effect of opioids on respiration in patients with advanced disease and chronic breathlessness was systematically […]

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Is the rationale more important than deception? A randomized controlled trial of open-label placebo analgesia. Locher C, Frey Nascimento A, Kirsch I, Kossowsky J, Meyer A, Gaab J. Pain. 2017 Dec;158(12):2320 2328. Healthy volunteers were recruited to an experimental heat pain analgesia randomized controlled trial. Forty healthy volunteers in each group were randomly assigned to […]

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Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data. Bally M, Dendukuri N, Rich B, Nadeau L, Helin-Salmivaara A, Garbe E, Brophy JM. BMJ. 2017 May 9;357:j1909. A bayesian meta-analysis of individual patient data from Canadian and European healthcare databases (61460 cases of acute myocardial infarction and […]

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C-reactive protein, symptoms and activity of daily living in patients with advanced cancer receiving palliative care. Amano K, Maeda I, Morita T, et al J Cachexia Sarcopenia Muscle. 2017 Jun;8(3):457-465. A secondary data analysis of a cross-sectional study looked at the associations between C-reactive protein (CRP) level, manual muscle testing of limbs, symptoms and activities […]

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Retrospective review of serotonergic medication tolerability in patients with neuroendocrine tumors with biochemically proven carcinoid syndrome. Shi DD, Yuppa DP, Dutton T, et al. Cancer. 2017 Jul 15;123(14):2735-2742 A retrospective review of patients with metastatic carcinoid tumours and elevated serotonin levels who received serotonergic antidepressants was performed to evaluate the effect of serotonergic antidepressants on […]

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Prevalence and incidence of chronic pain with or without neuropathic characteristics in patients with cancer. Bouhassira D, Luporsi E, Krakowski I. Pain. 2017 Jun;158(6):1118-1125. A prospective observational study in France recruited 1805 cancer patients attending out-patients for cancer treatment from 12 oncology units. A clinical examination, DN4 questionnaire and Brief Pain Inventory were used to […]

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Cost analysis of a prospective multi-site cohort study of palliative care consultation teams for adults with advanced cancer: Where do cost-savings come from? May P, Garrido MM, Cassel JB, Kelley AS, Meier DE, Normand C, Smith TJ, Morrison RS. Palliat Med. 2017 Apr;31(4):378-386.   A prospective multi-site cohort study in three US hospitals included 863 […]

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Comparing the symptom experience of cancer patients and non-cancer patients. Deshields TL, Penalba V, Liu J, Avery J. Support Care Cancer. 2017 Apr;25(4):1103-1109.   This study focussed on symptom burden of 301 consecutive patients from a general medical clinic and 558 cancer patients from a tumour registry who completed the Memorial Symptom Assessment Scale. Results […]

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