Cases and controls

I’ve noticed that there are a fair few phrases in the world where there actual meaning can be unclear or uncertain, or possibly interpreted differently by folk. Take “maybe later” when used by parent to child – clearly means “no” to the parent and “yes but not now” to the child. Or “brexit”. But the […]

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StatsMiniBlog: Pants and primary schools.

I’ve been struggling to get the concept behind random-effects meta-analysis out for some time – it’s the ‘average effectiveness’ in an ‘average population’ – with the prediction interval being the ‘actual width of where the truth might lie’. But .. yes .. but what does that actually mean & why does that matter? Well. Take a […]

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Hard science in difficult areas

It’s one of the delights of my professional clinical practice that (nearly) all the time, the diagnosis of a malignancy is hard & sound, reproducible, based on good data showing discrimination from other settings and with minimal interpersonal variation. Take a chunk of a particular renal tumour and show it to half a dozen paeds pathologists, […]

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How the magic works

It’s become fairly clear that most people don’t really know how articles get from the pen into the ‘accepted’ queue at a journal. At the most wonderful paediatric / child health journal on the planet (*) the process works like this: * ADC of course! […]

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Vague, unsure or imprecise?

Trials and tribulations we all have. The not-knowing of the future can create anxiety, distress and an unhealthy desire for chocolate. Some days, knowing what’s for tea can provide the only concrete grounding in an otherwise fluctuant universe. And along with that, the naming of things can sometimes be enlightening. So, for un-knowing, you could […]

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ADCE3 – Nothing seems right

 There are some times when it seems that no decision can be the right decision but doing nothing is as much as a decision as doing something. Admittedly, it’s rare you’re faced with shooting a killer in cold blood to prevent him murdering a not-so-innocent man. But sometimes the triadic nature of paediatric & adolescent […]

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