{"id":857,"date":"2013-11-11T09:00:22","date_gmt":"2013-11-11T09:00:22","guid":{"rendered":"http:\/\/stg-blogs.bmj.com\/spcare\/?p=857"},"modified":"2013-10-21T09:10:05","modified_gmt":"2013-10-21T09:10:05","slug":"shortcuts-18","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/spcare\/2013\/11\/11\/shortcuts-18\/","title":{"rendered":"SHORTCUTS"},"content":{"rendered":"<p>Shortcuts November 2013<\/p>\n<p>&nbsp;<\/p>\n<p><strong>J Palliat Med. 2013 Jul;16(7):741-4<\/strong><\/p>\n<p><a href=\"http:\/\/online.liebertpub.com\/doi\/abs\/10.1089\/jpm.2012.0505\" target=\"_blank\"><strong>The Role of Benzodiazepines in Breathlessness: A Single Site, Open Label Pilot of Sustained Release Morphine Together with Clonazepam<\/strong><\/a><\/p>\n<p><strong>Allcroft P, Margitanovic V, Greene A, Agar MR, Clark K, Abernethy AP, Currow DC<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>This single site, open label pilot study assessed the safety and feasibility of adding regular clonazepam 0.5\u2009mg nocte to regular oral 10\u2009mg sustained release morphine sulphate mane in 11 people with COPD and intensity of breathlessness \u22652 on the modified Medical Research Council Scale. Ten people completed four days (the efficacy outcome), five of whom reached the 15% reduction target in their baseline breathlessness intensity and three went on to the 10 day extension study, none of whom had adverse events. In view of these preliminary safety findings and the common use of Benzodiazepines for this indication, the authors suggest that a larger controlled trial is warranted.<\/p>\n<p>DOI: 10.1089\/jpm.2012.0505<\/p>\n<p>&nbsp;<\/p>\n<p><em>by Jason Boland<\/em><!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Shortcuts November 2013 &nbsp; J Palliat Med. 2013 Jul;16(7):741-4 The Role of Benzodiazepines in Breathlessness: A Single Site, Open Label Pilot of Sustained Release Morphine Together with Clonazepam Allcroft P, Margitanovic V, Greene A, Agar MR, Clark K, Abernethy AP, Currow DC &nbsp; This single site, open label pilot study assessed the safety and feasibility [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/spcare\/2013\/11\/11\/shortcuts-18\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":201,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1982],"tags":[],"class_list":["post-857","post","type-post","status-publish","format-standard","hentry","category-short-cuts"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/posts\/857","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/users\/201"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/comments?post=857"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/posts\/857\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/media?parent=857"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/categories?post=857"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/tags?post=857"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}