{"id":484,"date":"2014-12-12T01:19:50","date_gmt":"2014-12-12T01:19:50","guid":{"rendered":"http:\/\/stg-blogs.bmj.com\/jnnp\/?p=484"},"modified":"2014-12-12T01:19:50","modified_gmt":"2014-12-12T01:19:50","slug":"neurodegeneration-in-ms-a-clue-to-diability","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/jnnp\/2014\/12\/12\/neurodegeneration-in-ms-a-clue-to-diability\/","title":{"rendered":"Neurodegeneration in MS:  A clue to diability?"},"content":{"rendered":"<p>Corticla tarophy has been proposed as an imprtant pathophysiological mechanisms in disability development in progressive forms of multiple sclerosis.\u00a0 A number of studies utilsing sophistcated MRI tehcniques have yielded such evidence.\u00a0 In this issue of JNNP and elegant study demonstrated the importance of neurodegeneration at a pathological level, &#8220;<strong><em>reflected by a global reduction of neuronal density, the presence of acutely injured axons, and the accumulation of oxidised phospholipids and DNA in neurons, oligodendrocytes and axons<\/em><\/strong>&#8220;.\u00a0 As such preventing degenration is the key, although the real question must be how can we revearse the process.\u00a0 Will antioxidants, antiexcitotoxic agents work??<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>Read more at http:\/\/jnnp.bmj.com\/content\/85\/12\/1386.abstract<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Corticla tarophy has been proposed as an imprtant pathophysiological mechanisms in disability development in progressive forms of multiple sclerosis.\u00a0 A number of studies utilsing sophistcated MRI tehcniques have yielded such evidence.\u00a0 In this issue of JNNP and elegant study demonstrated the importance of neurodegeneration at a pathological level, &#8220;reflected by a global reduction of neuronal [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/jnnp\/2014\/12\/12\/neurodegeneration-in-ms-a-clue-to-diability\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-484","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/posts\/484","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/comments?post=484"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/posts\/484\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/media?parent=484"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/categories?post=484"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/tags?post=484"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}