{"id":431,"date":"2014-08-06T12:15:52","date_gmt":"2014-08-06T12:15:52","guid":{"rendered":"http:\/\/stg-blogs.bmj.com\/jnnp\/?p=431"},"modified":"2014-08-06T12:15:52","modified_gmt":"2014-08-06T12:15:52","slug":"glutamate-and-memory-a-novel-paradigm-in-ms","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/jnnp\/2014\/08\/06\/glutamate-and-memory-a-novel-paradigm-in-ms\/","title":{"rendered":"Glutamate and memory: A novel paradigm in MS"},"content":{"rendered":"<p>Glutamate is a major excitatory\u00a0 neurotransmitter in the human brain vital for multiple functions, including memory and cognition.\u00a0 Importantly, excessive glutamate activity may be harmful<\/p>\n<p>to the CNS, leading to neurodegeneration.\u00a0 In this issue of JNNP, Muhlert and colleagues report a link between glutamate levels and memory, a unique link in MS.\u00a0 Given that forgetfulness is a common symptom in MS, the possibility of using glutamate agonist, or enhancer of the glutamatergic system,\u00a0\u00a0 has real potential.<\/p>\n<p>&nbsp;<\/p>\n<p>Read more at :\u00a0 http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract<\/p>\n<h1 id=\"article-title-1\">Memory in multiple sclerosis is linked to glutamate concentration in grey matter regions<\/h1>\n<p><span class=\"open-access-note\"><a href=\"http:\/\/jnnp.bmj.com\/site\/about\/unlocked.xhtml\"><img loading=\"lazy\" decoding=\"async\" title=\"Open Access\" src=\"http:\/\/jnnp.bmj.com\/publisher\/icons\/open-access-logo.gif\" alt=\"Open Access\" width=\"116\" height=\"20\" \/><\/a><\/span><\/p>\n<div class=\"contributors\">\n<ol id=\"contrib-group-1\" class=\"contributor-list\">\n<li id=\"contrib-1\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Nils+Muhlert&amp;sortspec=date&amp;submit=Submit\">Nils Muhlert<\/a><\/span><a id=\"xref-aff-1-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-1\">1<\/a><span class=\"xref-sep\">,<\/span><a id=\"xref-aff-2-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-2\">2<\/a>,<\/li>\n<li id=\"contrib-2\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Matteo+Atzori&amp;sortspec=date&amp;submit=Submit\">Matteo Atzori<\/a><\/span><a id=\"xref-aff-3-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-3\">3<\/a><span class=\"xref-sep\">,<\/span><a id=\"xref-aff-4-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-4\">4<\/a>,<\/li>\n<li id=\"contrib-3\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Enrico+De+Vita&amp;sortspec=date&amp;submit=Submit\">Enrico De Vita<\/a><\/span><a id=\"xref-aff-5-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-5\">5<\/a><span class=\"xref-sep\">,<\/span><a id=\"xref-aff-6-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-6\">6<\/a>,<\/li>\n<li id=\"contrib-4\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=David+L+Thomas&amp;sortspec=date&amp;submit=Submit\">David L Thomas<\/a><\/span><a id=\"xref-aff-6-2\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-6\">6<\/a>,<\/li>\n<li id=\"contrib-5\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Rebecca+S+Samson&amp;sortspec=date&amp;submit=Submit\">Rebecca S Samson<\/a><\/span><a id=\"xref-aff-1-2\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-1\">1<\/a>,<\/li>\n<li id=\"contrib-6\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Claudia+A+M+Wheeler-Kingshott&amp;sortspec=date&amp;submit=Submit\">Claudia A M Wheeler-Kingshott<\/a><\/span><a id=\"xref-aff-1-3\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-1\">1<\/a>,<\/li>\n<li id=\"contrib-7\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Jeroen+J+G+Geurts&amp;sortspec=date&amp;submit=Submit\">Jeroen J G Geurts<\/a><\/span><a id=\"xref-aff-7-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-7\">7<\/a>,<\/li>\n<li id=\"contrib-8\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=David+H+Miller&amp;sortspec=date&amp;submit=Submit\">David H Miller<\/a><\/span><a id=\"xref-aff-1-4\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-1\">1<\/a><span class=\"xref-sep\">,<\/span><a id=\"xref-aff-8-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-8\">8<\/a>,<\/li>\n<li id=\"contrib-9\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Alan+J+Thompson&amp;sortspec=date&amp;submit=Submit\">Alan J Thompson<\/a><\/span><a id=\"xref-aff-3-2\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-3\">3<\/a><span class=\"xref-sep\">,<\/span><a id=\"xref-aff-8-2\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-8\">8<\/a>,<\/li>\n<li id=\"contrib-10\" class=\"last\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Olga+Ciccarelli&amp;sortspec=date&amp;submit=Submit\">Olga Ciccarelli<\/a><\/span><a id=\"xref-aff-3-3\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-3\">3<\/a><span class=\"xref-sep\">,<\/span><a id=\"xref-aff-8-3\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract#aff-8\">8<\/a><\/li>\n<\/ol>\n<\/div>\n<p>&nbsp;<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Glutamate is a major excitatory\u00a0 neurotransmitter in the human brain vital for multiple functions, including memory and cognition.\u00a0 Importantly, excessive glutamate activity may be harmful to the CNS, leading to neurodegeneration.\u00a0 In this issue of JNNP, Muhlert and colleagues report a link between glutamate levels and memory, a unique link in MS.\u00a0 Given that forgetfulness [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/jnnp\/2014\/08\/06\/glutamate-and-memory-a-novel-paradigm-in-ms\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-431","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/posts\/431","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/comments?post=431"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/posts\/431\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/media?parent=431"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/categories?post=431"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jnnp\/wp-json\/wp\/v2\/tags?post=431"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}