{"id":793,"date":"2015-08-21T18:40:43","date_gmt":"2015-08-21T18:40:43","guid":{"rendered":"http:\/\/stg-blogs.bmj.com\/jmg\/?p=793"},"modified":"2015-08-21T18:40:43","modified_gmt":"2015-08-21T18:40:43","slug":"hereditary-diffuse-gastric-cancer-updated-clinical-guidelines-with-an-emphasis-on-germline-cdh1-mutation-carriers","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/jmg\/2015\/08\/21\/hereditary-diffuse-gastric-cancer-updated-clinical-guidelines-with-an-emphasis-on-germline-cdh1-mutation-carriers\/","title":{"rendered":"Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers"},"content":{"rendered":"<p>In March 2014 the International Gastric Cancer Linkage Consortium, a group of worldwide experts in the field of Hereditary Diffuse Gastric Cancer, held a consensus meeting in the Radboudumc in Nijmegen, The Netherlands. During this three-day meeting, the current evidence and world-wide experience for managing individuals with a family history of diffuse type gastric cancer was discussed. New criteria for <em>CDH1<\/em> mutation testing, as well as updated endoscopy screening and surveillance protocols are described in the revised guideline. Additionally, the treatment of carriers of germline <em>CDH1<\/em> mutations are extensively discussed including prophylactic surgery as well as nutritional and psychological needs. (By Dr. Ingrid Vogelaar, <a href=\"http:\/\/jmg.bmj.com\/content\/52\/6\/361\">http:\/\/jmg.bmj.com\/content\/52\/6\/361<\/a> )<\/p>\n<p><a href=\"https:\/\/stg-blogs.bmj.com\/jmg\/files\/2015\/08\/IGCLC_group_picture.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-794\" src=\"https:\/\/stg-blogs.bmj.com\/jmg\/files\/2015\/08\/IGCLC_group_picture-300x175.jpg\" alt=\"IGCLC_group_picture\" width=\"300\" height=\"175\" srcset=\"https:\/\/stg-blogs.bmj.com\/jmg\/files\/2015\/08\/IGCLC_group_picture-300x175.jpg 300w, https:\/\/stg-blogs.bmj.com\/jmg\/files\/2015\/08\/IGCLC_group_picture-1024x598.jpg 1024w, https:\/\/stg-blogs.bmj.com\/jmg\/files\/2015\/08\/IGCLC_group_picture.jpg 1512w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>The IGCLC group<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In March 2014 the International Gastric Cancer Linkage Consortium, a group of worldwide experts in the field of Hereditary Diffuse Gastric Cancer, held a consensus meeting in the Radboudumc in Nijmegen, The Netherlands. During this three-day meeting, the current evidence and world-wide experience for managing individuals with a family history of diffuse type gastric cancer [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/jmg\/2015\/08\/21\/hereditary-diffuse-gastric-cancer-updated-clinical-guidelines-with-an-emphasis-on-germline-cdh1-mutation-carriers\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-793","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/posts\/793","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/comments?post=793"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/posts\/793\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/media?parent=793"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/categories?post=793"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/tags?post=793"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}