{"id":792,"date":"2015-08-05T16:00:51","date_gmt":"2015-08-05T16:00:51","guid":{"rendered":"http:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/?p=792"},"modified":"2017-08-21T11:42:15","modified_gmt":"2017-08-21T11:42:15","slug":"primary-care-corner-with-geoffrey-modest-md-arthroscopic-surgery-for-knee-oa","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/2015\/08\/05\/primary-care-corner-with-geoffrey-modest-md-arthroscopic-surgery-for-knee-oa\/","title":{"rendered":"Primary Care Corner with Geoffrey Modest MD: Arthroscopic surgery for knee OA???"},"content":{"rendered":"<p><strong>By: Dr. Geoffrey Modest<\/strong><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: black\">There have been a couple of well-publicized studies finding that arthroscopic knee surgery for degenerative joint disease\/osteoarthritis (OA) is not beneficial. However, there continues to be uncertainty, and &#8220;many specialists are convinced of the benefits of the procedure from their own experience&#8221;. \u00a0In the US, 700K knee\u00a0arthroscopies are done each year, and this number seems to be increasing. In this light, there is a welcome systematic review and meta-analysis just published <\/span><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">(see <a href=\"http:\/\/dx.doi.org\/10.1136\/bmj.h2747\">here<\/a>). \u00a0<\/span><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">Details, for the 9 studies evaluated:<\/span><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">&#8211;1270 patients in total,\u00a0receiving\u00a0arthroscopic surgery with partial meniscectomy, debridement or both, vs control (sham surgery or exercise)<\/span><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">&#8211;Mean age in the studies was 49.7-62.8. mean baseline pain (visual analog scale of 0-100mm) ranged from 36-63 mm.<\/span><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">&#8211;2 trials only had patients with radiologic OA (Kallgren and Lawrence grade 2 or more); 5 trials had some patients with radiologic OA; and 2 trials had patients without xray changes.<\/span><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">&#8211;Time to primary endpoints in the studies\u00a0varied from 3-24 months.<\/span><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">Results:<\/span><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">&#8211;Overall there was a small but statistically significant reduction in pain with arthroscopy (a difference of 2.4 mm on the visual analog scale), and only at 3 and 6 months, but not at subsequent evaluations. For reference, it is typically suggested that a change of 15-20 mm is likely to be clinically relevant.<\/span><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">&#8211;No difference in physical function at any time-period\u00a0between\u00a0arthroscopy vs control<\/span><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">&#8211;Subgroup analysis:<\/span><\/p>\n<p style=\"padding-left: 30px\"><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">&#8211;no difference if there are xray changes of OA or not<\/span><\/p>\n<p style=\"padding-left: 30px\"><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">&#8211;no difference\u00a0by type of surgery (partial meniscectomy with\u00a0or without concomitant debridement) vs control<\/span><\/p>\n<p style=\"padding-left: 30px\"><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">&#8211;no difference by study design (sham surgery vs exercise for the control arm &#8212; and, one might think that surgery would have more of a placebo effect than exercise\u00a0as the control)<\/span><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">\u200b&#8211;Harms of surgery: DVT was most frequent, at 4.13 per 1000 procedures. followed by infection, pulmonary embolism, and death (death in 0.96\/1000 procedures).<\/span><\/p>\n<p><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\"><span style=\"color: #000000\">A<\/span><\/span><span style=\"font-size: 11.0pt;font-family: 'Calibri',sans-serif;color: #333333;background: white\">s we know, knee DJD is really common with aging, causes lots of disability, yet our diagnostic approaches are inadequate\u00a0(the longitudinal studies, such as the Framingham Study, found a poor correlation between xrays and symptoms &#8212; such that some reviews do not suggest getting routine xrays). In addition, the more revealing\u00a0MRI exams show that cartilage and meniscus\u00a0degeneration typical of OA can be found commonly in people without knee symptoms. \u00a0I am bringing up the current meta-analysis\/systematic review because it reinforces the\u00a0clinically insignificant benefit of surgery (though with attendant harms). \u00a0And, to me, one of our most important roles in primary care is to be a strong advocate for our patients &#8212; so, for example,\u00a0if we send a patient to an\u00a0orthopedist for evaluation for knee replacement surgery and the orthopedist suggests arthroscopy based on OA with degenerative meniscal tears, this study supports our advising the patient to be evaluated by another orthopedist&#8230;.<\/span><span style=\"font-family: 'Calibri',sans-serif;color: black\">\u200b<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>By: Dr. Geoffrey Modest There have been a couple of well-publicized studies finding that arthroscopic knee surgery for degenerative joint disease\/osteoarthritis (OA) is not beneficial. However, there continues to be uncertainty, and &#8220;many specialists are convinced of the benefits of the procedure from their own experience&#8221;. \u00a0In the US, 700K knee\u00a0arthroscopies are done each year, [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/2015\/08\/05\/primary-care-corner-with-geoffrey-modest-md-arthroscopic-surgery-for-knee-oa\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":148,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[14283],"tags":[],"class_list":["post-792","post","type-post","status-publish","format-standard","hentry","category-archive"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/wp-json\/wp\/v2\/posts\/792","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/wp-json\/wp\/v2\/users\/148"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/wp-json\/wp\/v2\/comments?post=792"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/wp-json\/wp\/v2\/posts\/792\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/wp-json\/wp\/v2\/media?parent=792"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/wp-json\/wp\/v2\/categories?post=792"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmjebmspotlight\/wp-json\/wp\/v2\/tags?post=792"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}