Jack O’Sullivan – BMJ EBM Spotlight

Five reasons why diagnostic studies fail

Posted on 6th December 201730th January 2018 by BMJ

The number of studies assessing the diagnostic accuracy of tests is growing rapidly, but many studies fail to impact on practice due to five fundamental flaws in their methods. Jack O’Sullivan Diagnostic accuracy studies aim to determine how good a new test is at diagnosing a disease compared with a current test. To do this, […]

Controversies in PSA screening

Posted on 19th October 20171st November 2017 by BMJ

40 years after its discovery, a re-analysis of the two largest trials to date, controversially suggests PSA screening may actually be beneficial. Jack O’Sullivan Most healthcare organisations do not recommend PSA screening for prostate cancer (USPSTF, Public Health England), mainly in response to conflicting evidence about the benefits and clear evidence of harms. PSA […]