recent update on prevention and treatment of opportunistic infections in HIV infected adolescents and adults.
reference: Panel on Opportunistic Infections in HIV-Infected Adults and Adolescents. Guidelines for the prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from the Centers for Disease Control and Prevention, the National Institutes of Health [trunc]. Atlanta (GA): Centers for Disease Control and Prevention (CDC); 2013 Jul 8.
on-line access: http://www.guideline.gov/content.aspx?f=rss&id=45359&osrc=12
some new info incorporated. the guidelines provide very specific recommendations, without a lot of text, for the myriad of HIV-related infections. a couple of notable changes:
–hep b. vaccination is as per non-HIV infected. important to check post-vaccination HbsAb to assess response. if non-responder, can wait til increase of CD4 if low, and then repeat; can give another series of vaccines; can give double dose vaccines (there have been a couple of articles in past year showing increased immunogenicity of the double-dose vaccine in HIV patients, so this is my preferred approach)
–hep c. includes use of protease inhibitors (boceprevir, telaprevir) along with interferon/ribivarin