{"id":32600,"date":"2014-10-24T17:16:22","date_gmt":"2014-10-24T16:16:22","guid":{"rendered":"http:\/\/stg-blogs.bmj.com\/bmj\/?p=32600"},"modified":"2017-01-31T09:36:16","modified_gmt":"2017-01-31T08:36:16","slug":"margaret-cooter-colour-me-unusual-a-mrsa-quilt-and-a-tb-dress","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/bmj\/2014\/10\/24\/margaret-cooter-colour-me-unusual-a-mrsa-quilt-and-a-tb-dress\/","title":{"rendered":"Margaret Cooter: Colour me unusual\u2014a MRSA quilt and a TB dress"},"content":{"rendered":"<p><a href=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/Margaret_Coote2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft  wp-image-32608\" src=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/Margaret_Coote2.jpg\" alt=\"Margaret_Coote2\" width=\"149\" height=\"155\" \/><\/a>On learning about the source of the colour of Anna Dumitriu\u2019s quilt, some people feel distinctly uncomfortable, and a few have even said, \u201cBut that\u2019s irresponsible! That\u2019s dangerous!\u201d<\/p>\n<p>The blue doesn\u2019t come from indigo or from a new type of powder\u2014and the way it\u2019s used is definitely not irresponsible or dangerous. Although the colour comes from MRSA bacteria (\u201csuperbugs\u201d), the colouring process was carried out in a laboratory, under optimal safety conditions.<!--more--><\/p>\n<p><a href=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/mrsa_quilt.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft  wp-image-32601\" src=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/mrsa_quilt-300x181.png\" alt=\"mrsa_quilt\" width=\"173\" height=\"104\" srcset=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/mrsa_quilt-300x181.png 300w, https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/mrsa_quilt.png 342w\" sizes=\"auto, (max-width: 173px) 100vw, 173px\" \/><\/a><em>MRSA Quilt (photo from <a href=\"http:\/\/annadumitriu.tumblr.com\/NormalFloraExhibition\">annadumitriu.tumblr.com\/NormalFloraExhibition<\/a>).\u00a0<\/em>Before leaving the lab, the fabric was treated at high temperatures to kill the bacteria. The bacteria are dyed blue because they are grown on chromogenic agar, which contains the dye and which soaks into the cloth. As the agar feeds the bacteria, they take up the dye, become blue, and colour the cloth.<\/p>\n<p><a href=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/dyeing.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft  wp-image-32602\" src=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/dyeing.png\" alt=\"dyeing\" width=\"212\" height=\"255\" \/><\/a><em>Dyeing in progress at a public workshop; the plates were taken back to the lab and grown with bacteria (photo from <a href=\"http:\/\/annadumitriu.tumblr.com\/post\/56324504323\/there-was-a-hugely-successful-and-widely-reported\">annadumitriu.tumblr.com<\/a>).<\/em><\/p>\n<p>The embroidery thread used in the quilt is coloured with safflower and turmeric\u2014and (in some cases) impregnated with the antibiotic vancomycin, which is considered to be a &#8220;last ditch&#8221; antibiotic for treating MRSA infection.<\/p>\n<p>Anna Dumitriu\u2019s unusual dyestuffs are an outcome of an ongoing artist in residence project\u2014initially funded by the Leverhulme Trust Artist in Residence Award in 2011, and by the Wellcome Trust and Arts Council England\u2014at the <a href=\"http:\/\/modmedmicro.nsms.ox.ac.uk\/\">Modernising Medical Microbiology Project<\/a> at the University of Oxford, in partnership with Public Health England. She works by shadowing scientists on the project, learning hands on techniques, and investigating their work.<\/p>\n<p>Anna\u2019s <a href=\"http:\/\/annadumitriu.tumblr.com\/RomanticDisease\">exhibition<\/a> in London earlier this year included other objects dyed with natural dyes: dyestuffs that were also used as medicines, or which perhaps became dyestuffs as a by-product of being used as medicines. Madder root for pink\/brown, safflower giving yellow or pink, and walnut husks for brown shades . . . these dyes were also used as ancient treatments for tuberculosis.<\/p>\n<p>Textile dyes are specifically involved in the history of drug treatment. In the 1930s, the dye company Bayer worked on the idea that coal tar dyes might be used to treat harmful substances in the body. The bacteriologist Gerhard Domagk came up with a bright orange substance that they called Prontosil, which, before antibiotics were widely developed, was hailed as a wonder drug and widely used in World War Two to prevent infection.<\/p>\n<p><a href=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/romanticdiseasedress.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft  wp-image-32604\" src=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/romanticdiseasedress-215x300.png\" alt=\"romanticdiseasedress\" width=\"176\" height=\"246\" srcset=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/romanticdiseasedress-215x300.png 215w, https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/romanticdiseasedress.png 226w\" sizes=\"auto, (max-width: 176px) 100vw, 176px\" \/><\/a><em>The Romantic Disease Dress (photo from <a href=\"http:\/\/theromanticdisease.tumblr.com\/dress\">theromanticdisease.tumblr.com\/dress<\/a>).<\/em><\/p>\n<p>Anna has used Prontosil to stain embroidery on the back shoulders of an antique maternity dress, which was impregnated with the extracted DNA of killed tuberculosis bacteria. She dyed the dress with walnut husks, and dyed the embroidery threads and ribbons with madder root and safflower.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/lungs.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft  wp-image-32605\" src=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/lungs.png\" alt=\"lungs\" width=\"241\" height=\"170\" \/><\/a><em>Where there\u2019s dust there\u2019s danger (photo from <a href=\"http:\/\/annadumitriu.tumblr.com\/RomanticDisease\">annadumitriu.tumblr.com\/RomanticDisease<\/a>).<\/em><\/p>\n<p>Also part of the project on tuberculosis (the world&#8217;s largest infectious killer) are little felted lungs. &#8220;Where there&#8217;s dust there&#8217;s danger,&#8221; advised the Society for the Prevention of Consumption in 1902 (incorrectly, as it turned out). Basing the lungs on this long held misconception, Anna made them with felting wool and household dust, then impregnated them\u2014as she had the antique dress\u2014with DNA that had been extracted from killed TB organisms. The DNA is dead so it\u2019s not harmful; there is no risk of infection from the little lungs, just a &#8220;memory&#8221; of being contaminated.<\/p>\n<p><a href=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/bed.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-32606\" src=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/bed-198x300.png\" alt=\"bed\" width=\"198\" height=\"300\" srcset=\"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/bed-198x300.png 198w, https:\/\/stg-blogs.bmj.com\/bmj\/files\/2014\/10\/bed.png 237w\" sizes=\"auto, (max-width: 198px) 100vw, 198px\" \/><\/a><em>Genius Germ (photo from <a href=\"http:\/\/theromanticdisease.tumblr.com\/GeniusGerm\">theromanticdisease.tumblr.com\/GeniusGerm<\/a>).<\/em><\/p>\n<p>A recent project, made especially for a show at the Picasso Museum in Barcelona, is inspired by Picasso\u2019s painting of about 1899, which shows a group of people around the bed of a very sick patient. An antique doll\u2019s bed from the same period has been altered and given a quilt, created using squares of natural dyed fabric and threads treated with antibiotics and antibacterials, and grown with environmental bacteria (the quilt has been sterilised by autoclaving). The antique crochet pillow has been dyed with walnut husks, and the bedstead patterned to indicate the patient\u2019s degenerating lung tissue.<\/p>\n<p>The use of germs, the dusty lungs, the MRSA quilt: all give rise to horror struck reactions. Part of Anna\u2019s purpose in making these art works through her scientific art residencies is to use these objects as a kind of storytelling and to involve viewers in health issues\u2014a way to spread not germs but knowledge.<\/p>\n<p>Anna Dumitriu&#8217;s exhibition &#8220;[micro]biologies I: the bacterial sublime&#8221; is on at\u00a0<a href=\"http:\/\/www.artlaboratory-berlin.org\/\">Art Laboratory Berlin<\/a>\u00a0until 30 November 2014.<\/p>\n<p><em>After two decades at <\/em>The BMJ<em> as a technical editor, <strong>Margaret Cooter<\/strong> went on to art school, obtaining an MA from Camberwell (University of the Arts London) in 2012.<\/em><\/p>\n<p>Competing interests: I have read and understood BMJ policy on declaration of interests and declare the following interests: none.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>On learning about the source of the colour of Anna Dumitriu\u2019s quilt, some people feel distinctly uncomfortable, and a few have even said, \u201cBut that\u2019s irresponsible! That\u2019s dangerous!\u201d The blue doesn\u2019t come from indigo or from a new type of powder\u2014and the way it\u2019s used is definitely not irresponsible or dangerous. Although the colour comes [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/bmj\/2014\/10\/24\/margaret-cooter-colour-me-unusual-a-mrsa-quilt-and-a-tb-dress\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[116],"tags":[],"class_list":["post-32600","post","type-post","status-publish","format-standard","hentry","category-editors-at-large"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/32600","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/comments?post=32600"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/32600\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/media?parent=32600"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/categories?post=32600"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/tags?post=32600"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}