{"id":30546,"date":"2013-12-20T17:03:16","date_gmt":"2013-12-20T16:03:16","guid":{"rendered":"http:\/\/stg-blogs.bmj.com\/bmj\/?p=30546"},"modified":"2013-12-20T17:03:16","modified_gmt":"2013-12-20T16:03:16","slug":"bmj-journals-research-highlights-20-december-2013","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/bmj\/2013\/12\/20\/bmj-journals-research-highlights-20-december-2013\/","title":{"rendered":"BMJ Journals research highlights\u201420 December 2013"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" alt=\"Research questions\" src=\"http:\/\/www.bmj.com\/site\/blog\/icons\/research-methods-and-reporting.jpg\" width=\"160\" height=\"110\" align=\"left\" \/><em>BMJ Journals research highlights is a regular round-up of research papers appearing in the BMJ Journals.<\/em><\/p>\n<p><a href=\"http:\/\/thorax.bmj.com\/content\/early\/2013\/06\/07\/thoraxjnl-2012-203175\"><strong>Use of inhaled corticosteroids and the risk of tuberculosis<\/strong><\/a><br \/>\nChang-Hoon Lee,\u00a0 Kyungjoo Kim,\u00a0 Min Kyung Hyun,\u00a0 Eun Jin Jang,\u00a0 Na Rae Lee,\u00a0 Jae-Joon Yim<br \/>\nThorax 2013;68:1105-1113 Published online first: 8 June 2013 doi:10.1136\/thoraxjnl-2012-203175<\/p>\n<p>We have previously highlighted the worrying increase in a number of respiratory infections in patients treated with high dose inhaled corticosteroids (ICS). <a href=\"http:\/\/thorax.bmj.com\/content\/early\/2013\/06\/07\/thoraxjnl-2012-203175\">Here we publish a report<\/a> that ICS increases TB risk in a moderate TB prevalence region. The authors did a nice job calculating dose equivalence of the various inhalers prescribed and used the data to show a dose response effect for both asthma and COPD. Unfortunately they were not able to report comparative safety related to the topical potency of the ICS prescribed. These are really worrying data, and underscore the need to be really sure your patient needs potent ICS before you prescribe them; potentially they divert money from more useful medications in developing world contexts, as well as actually doing harm.<!--more--><\/p>\n<p><a href=\"http:\/\/oem.bmj.com\/content\/70\/12\/831.full\"><strong>Increased risk of breast cancer associated with long-term shift work in Canada<\/strong><\/a><br \/>\nAnne Grundy,\u00a0 Harriet Richardson,\u00a0 Igor Burstyn,\u00a0 Caroline Lohrisch,\u00a0 Sandip K SenGupta, Agnes S Lai,\u00a0 Derrick Lee,\u00a0 John J Spinelli,\u00a0 Kristan J Aronson<br \/>\nOccup Environ Med 2013;70:831-838 Published online first: 1 July 2013 doi:10.1136\/oemed-2013-101482<\/p>\n<p>Night shift work has been classified by the International Agency for Research on Cancer as a probable human carcinogen, although the mechanism remains unclear.\u00a0 This Canadian study progresses our knowledge as it found an association between long term night shift work and breast cancer in a broader range of occupations than previously reported, but no interaction with eostrogen receptor status.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>BMJ Journals research highlights is a regular round-up of research papers appearing in the BMJ Journals. Use of inhaled corticosteroids and the risk of tuberculosis Chang-Hoon Lee,\u00a0 Kyungjoo Kim,\u00a0 Min Kyung Hyun,\u00a0 Eun Jin Jang,\u00a0 Na Rae Lee,\u00a0 Jae-Joon Yim Thorax 2013;68:1105-1113 Published online first: 8 June 2013 doi:10.1136\/thoraxjnl-2012-203175 We have previously highlighted the worrying [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/bmj\/2013\/12\/20\/bmj-journals-research-highlights-20-december-2013\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-30546","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/30546","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/comments?post=30546"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/30546\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/media?parent=30546"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/categories?post=30546"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/tags?post=30546"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}