{"id":191,"date":"2007-04-16T13:00:45","date_gmt":"2007-04-16T12:00:45","guid":{"rendered":"http:\/\/resource.bmj.com\/bmj\/2007\/04\/16\/bmj-14-apr-2007\/"},"modified":"2007-04-16T13:00:45","modified_gmt":"2007-04-16T12:00:45","slug":"bmj-14-apr-2007","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/bmj\/2007\/04\/16\/bmj-14-apr-2007\/","title":{"rendered":"BMJ  14 Apr 2007"},"content":{"rendered":"<p>786   Several years ago, Philip Poole-Wilson issued a warning that too many cardiovascular trials use composite end-points and that this can seriously distort their conclusions.<!--more-->The warning has been repeated many times since, but does it still happen? You bet it does, but you will find more about current practice in the <a href=\"http:\/\/www.bmj.com\/cgi\/reprint\/334\/7597\/756\">editorial<\/a> than in this <a href=\"http:\/\/www.bmj.com\/cgi\/reprint\/334\/7597\/786\">systematic review<\/a> which only covers certain journals from Jan 2002 to June 2003. Still, <a href=\"http:\/\/www.bmj.com\/cgi\/reprint\/334\/7597\/786\">this paper<\/a> is good for categorising variability of effect according to importance to patients.<\/p>\n<p>Most people exposed to intensely traumatic events recover sufficiently to get on with life; otherwise Europe, Russia, China and Japan would have ceased to exist after 1945. But many are scarred and some remain incapacitated by post traumatic stress disorder. <a href=\"http:\/\/www.bmj.com\/cgi\/content\/extract\/334\/7597\/789\">Here <\/a>is a clear and pragmatic account of our present state of understanding and the current NICE guideline.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>786 Several years ago, Philip Poole-Wilson issued a warning that too many cardiovascular trials use composite end-points and that this can seriously distort their conclusions. [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/bmj\/2007\/04\/16\/bmj-14-apr-2007\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":38363,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[111],"tags":[],"class_list":["post-191","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-richard-lehmans-weekly-review-of-medical-journals"],"jetpack_featured_media_url":"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2017\/02\/richard-lehman.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/191","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/comments?post=191"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/191\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/media\/38363"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/media?parent=191"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/categories?post=191"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/tags?post=191"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}