{"id":140,"date":"2007-03-12T10:18:42","date_gmt":"2007-03-12T09:18:42","guid":{"rendered":"http:\/\/resource.bmj.com\/bmj\/2007\/03\/12\/ann-intern-med-6-mar-2007-vol-146\/"},"modified":"2007-03-12T10:18:42","modified_gmt":"2007-03-12T09:18:42","slug":"ann-intern-med-6-mar-2007-vol-146","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/bmj\/2007\/03\/12\/ann-intern-med-6-mar-2007-vol-146\/","title":{"rendered":"Ann Intern Med  6 Mar 2007  Vol 146"},"content":{"rendered":"<p>Population studies in the developed world generally find that about 20-25% of us are anxious and\/or depressed, and that is what this US study found when it used a number of assessment tools plus direct patient assessment to <a href=\"http:\/\/www.annals.org\/cgi\/content\/abstract\/146\/5\/317\">detect anxiety disorders in primary care<\/a>. <!--more-->The GAD-7 scale is pretty simple and reliable, and the first two questions alone (GAD-2: feeling nervous, anxious, or on edge, and not being able to stop or control worrying) pick up pretty well everyone with anxiety. By gad, I can\u2019t stop worrying &#8211; about having to give drugs to my patients because I can\u2019t get them cognitive behavioural therapy.If you were or indeed are a postmenopausal woman with low bone mineral density, which would you go for \u2013 a daily injection which causes nausea in a quarter of patients, a tablet once a week, or just daily calcium and vitamin D? It\u2019s a bit of a no-brainer, you\u2019d have thought, but the manufacturers of <a href=\"http:\/\/www.annals.org\/cgi\/content\/abstract\/146\/5\/326\">recombinant human parathyroid hormone<\/a> (teriparatide injection) managed to get this study past a great number of ethics committees and enrolled 2532 women from 168 centres and followed them up for 18 months, by which time a third had dropped out. Sure, teriparatide has an effect: it\u2019s impossible to quantify, thanks to the drop-out rate, and it\u2019s hard to see how the drug can ever compete with bisphosphonates and strontium.<\/p>\n<p>How can you evaluate a diagnostic test when there is no gold standard? That\u2019s the problem with tests for \u201cheart failure<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Population studies in the developed world generally find that about 20-25% of us are anxious and\/or depressed, and that is what this US study found when it used a number of assessment tools plus direct patient assessment to detect anxiety disorders in primary care. [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/bmj\/2007\/03\/12\/ann-intern-med-6-mar-2007-vol-146\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":38363,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[111],"tags":[],"class_list":["post-140","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-richard-lehmans-weekly-review-of-medical-journals"],"jetpack_featured_media_url":"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2017\/02\/richard-lehman.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/140","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/comments?post=140"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/140\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/media\/38363"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/media?parent=140"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/categories?post=140"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/tags?post=140"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}