{"id":100,"date":"2007-01-29T12:19:20","date_gmt":"2007-01-29T11:19:20","guid":{"rendered":"http:\/\/resource.bmj.com\/bmj\/2007\/01\/29\/arch-intern-med-22-jan-2007\/"},"modified":"2007-01-29T12:19:20","modified_gmt":"2007-01-29T11:19:20","slug":"arch-intern-med-22-jan-2007","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/bmj\/2007\/01\/29\/arch-intern-med-22-jan-2007\/","title":{"rendered":"Arch Intern Med 22 Jan 2007"},"content":{"rendered":"<p>A <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/117\">review<\/a> that looks at randomised controlled trials comparing <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/117\">oral anticoagulation<\/a> with and without <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/117\">added aspirin<\/a> in various clinical contexts. In all of them except patients with <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/117\">mechanical heart valves<\/a>, there is little evidence of clinical benefit and lots of extra bleeding.  Here\u2019s a <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/133\">paper<\/a> which combines two QOF areas which have caused much exasperation to British GPs struggling to get home in the evening with their bags of money: <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/133\">eGFR and fracture risk<\/a>.<!--more--> Now most of us have reached the conclusion that an eGFR between 45 and 60 in a woman aged 65 or more is unimportant, but in fact it is associated with a significant added risk of <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/133\">hip fracture<\/a>, though not of vertebral fracture. This risk increases as renal function worsens, does not apply to vertebral fractures, and may not be mediated by osteoporosis. <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/148\">Selenium<\/a> is a moony enigmatic element lying on the border between metals and non-metals and is also good for us in enigmatic ways. Selenium supplementation seems to suppress the viral load of <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/148\">human immunodeficiency virus type 1<\/a>; we also know that it may prevent prostate cancer. is a moony enigmatic element lying on the border between metals and non-metals and is also good for us in enigmatic ways. Selenium supplementation seems to suppress the viral load of ; we also know that it may prevent prostate cancer. How often should we be measuring <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/155\">bone mineral density<\/a> in healthy <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/155\">older postmenopausal women?<\/a> From the USA, where every scan brings bucks, the reassuring message is <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/155\">once only<\/a>. Further scans after 8 years didn\u2019t help to predict fracture risk in this cohort (mean age 72). Here\u2019s a multi-ethnic <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/174\">study<\/a> of atherosclerosis which looks at the relationship between <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/174\">psychosocial factors and inflammation<\/a>. The strongest factor linking the two is <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/174\">cynical mistrust<\/a>. Sorry, readers: by sending you these reviews, I may be helping to kill you.<\/p>\n<p>is a moony enigmatic element lying on the border between metals and non-metals and is also good for us in enigmatic ways. Selenium supplementation seems to suppress the viral load of ; we also know that it may prevent prostate cancer. Now here\u2019s the news you may have heard but didn\u2019t want to hear: <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/188\">serotonin reuptake inhibitors<\/a> may <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/167\/2\/188\">double fracture risk<\/a> in people over 50. This was, however, a small study and although it adjusted for \u201cpotential covariate<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A review that looks at randomised controlled trials comparing oral anticoagulation with and without added aspirin in various clinical contexts. In all of them except patients with mechanical heart valves, there is little evidence of clinical benefit and lots of extra bleeding. Here\u2019s a paper which combines two QOF areas which have caused much exasperation [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/bmj\/2007\/01\/29\/arch-intern-med-22-jan-2007\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":38363,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[111],"tags":[],"class_list":["post-100","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-richard-lehmans-weekly-review-of-medical-journals"],"jetpack_featured_media_url":"https:\/\/stg-blogs.bmj.com\/bmj\/files\/2017\/02\/richard-lehman.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/100","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/comments?post=100"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/100\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/media\/38363"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/media?parent=100"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/categories?post=100"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/tags?post=100"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}