{"id":849,"date":"2014-02-12T21:20:06","date_gmt":"2014-02-12T20:20:06","guid":{"rendered":"http:\/\/stg-blogs.bmj.com\/adc\/?p=849"},"modified":"2014-02-05T21:09:33","modified_gmt":"2014-02-05T20:09:33","slug":"statsminiblog-subgroup-or-sensitivity-analyses","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/adc\/2014\/02\/12\/statsminiblog-subgroup-or-sensitivity-analyses\/","title":{"rendered":"StatsMiniBlog: Subgroup or sensitivity analyses?"},"content":{"rendered":"<p><a href=\"https:\/\/stg-blogs.bmj.com\/adc\/files\/2014\/02\/20140205-091454.jpg\"><img decoding=\"async\" src=\"https:\/\/stg-blogs.bmj.com\/adc\/files\/2014\/02\/20140205-091454.jpg\" alt=\"20140205-091454.jpg\" class=\"alignnone size-full\" \/><\/a><\/p>\n<p>Perhaps becoming a little obscure, but there are some folk in the world who become concerned about undertaking analysis in systematic reviews.<\/p>\n<p>Some of these are described as &#8220;subgroup&#8221; analysis, others &#8220;sensitivity&#8221;. What&#8217;s the difference, and why?<\/p>\n<p><!--more--><\/p>\n<p>Simply put &#8211; there&#8217;s often little difference. But a practical differentiation might go along the lines of<\/p>\n<p>Subgroup analysis (or meta-regression): &#8220;How might this [intervention] have a different effect in different groups&#8221; e.g. different ages of patient, or different type of quinolone, or different diagnostic classification of disease<\/p>\n<p>Sensitivity analysis: &#8220;How might our analysis be affected by something in the assumptions we have made?&#8221; e.g. lumping high and low quality studies together, regarding outcomes at 15 and 30 days as equivalent, or using fixed vs. random effects meta-analysis<\/p>\n<p>&#8211; Archi<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Perhaps becoming a little obscure, but there are some folk in the world who become concerned about undertaking analysis in systematic reviews. Some of these are described as &#8220;subgroup&#8221; analysis, others &#8220;sensitivity&#8221;. What&#8217;s the difference, and why? [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/adc\/2014\/02\/12\/statsminiblog-subgroup-or-sensitivity-analyses\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[2676],"tags":[],"class_list":["post-849","post","type-post","status-publish","format-standard","hentry","category-stats"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/posts\/849","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/comments?post=849"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/posts\/849\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/media?parent=849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/categories?post=849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/tags?post=849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}