{"id":13,"date":"2007-07-30T12:01:01","date_gmt":"2007-07-30T11:01:01","guid":{"rendered":"http:\/\/resource.bmj.com\/adc-archimedes\/2007\/07\/30\/unanswered-question-is-ldh-a-good-predictor-of-malignancy-in-children\/"},"modified":"2007-07-30T12:01:01","modified_gmt":"2007-07-30T11:01:01","slug":"unanswered-question-is-ldh-a-good-predictor-of-malignancy-in-children","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/adc\/2007\/07\/30\/unanswered-question-is-ldh-a-good-predictor-of-malignancy-in-children\/","title":{"rendered":"Unanswered Question: Is LDH a good predictor of malignancy in children?"},"content":{"rendered":"<p>A four-year old girl presents to the accident and emergency department with a history of being generally unwell for the preceding week and on examination is found to have cervical lymphadenopathy. In addition to a volley of tests, a Lactate Dehydrogenase (LDH) was requested by a registrar who had read that this was a predictor of malignancy which came back as 1,750. Should this be seen as suggestive of underlying malignancy? <!--more--><\/p>\n<p>Report by:<\/p>\n<p>Tauseef Mehrali (SHO), Birmingham Children\u2019s Hospital<\/p>\n<p>How often have you  seen a child with a neck full of lymph nodes, sent an LDH and been concerned about lymphoma? It&#8217;s a frequent occurrence in my clinical practise (although I am a Paeds Oncologists in between Archimedes topics). And I do fret about them &#8211; but should I be? (At a rough guess, my pre-test probability of lymphoma is about 75%; probably a fair bit higher than the ED experience.) What do the rest of you do, or think?<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A four-year old girl presents to the accident and emergency department with a history of being generally unwell for the preceding week and on examination is found to have cervical lymphadenopathy. In addition to a volley of tests, a Lactate Dehydrogenase (LDH) was requested by a registrar who had read that this was a predictor [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/adc\/2007\/07\/30\/unanswered-question-is-ldh-a-good-predictor-of-malignancy-in-children\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[81,99],"tags":[],"class_list":["post-13","post","type-post","status-publish","format-standard","hentry","category-diagnostics","category-oncology"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/posts\/13","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/comments?post=13"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/posts\/13\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/media?parent=13"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/categories?post=13"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/tags?post=13"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}