{"id":1197,"date":"2015-11-17T20:55:57","date_gmt":"2015-11-17T19:55:57","guid":{"rendered":"http:\/\/stg-blogs.bmj.com\/adc\/?p=1197"},"modified":"2015-11-14T21:34:22","modified_gmt":"2015-11-14T20:34:22","slug":"interventions-without-evidence-should-not-be-undertaken-discuss","status":"publish","type":"post","link":"https:\/\/stg-blogs.bmj.com\/adc\/2015\/11\/17\/interventions-without-evidence-should-not-be-undertaken-discuss\/","title":{"rendered":"Interventions without evidence should not be undertaken. Discuss."},"content":{"rendered":"<p><a href=\"https:\/\/stg-blogs.bmj.com\/adc\/files\/2015\/11\/1024px-Debate_Logo.svg_.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft  wp-image-1198\" src=\"https:\/\/stg-blogs.bmj.com\/adc\/files\/2015\/11\/1024px-Debate_Logo.svg_-300x209.png\" alt=\"1024px-Debate_Logo.svg\" width=\"244\" height=\"170\" srcset=\"https:\/\/stg-blogs.bmj.com\/adc\/files\/2015\/11\/1024px-Debate_Logo.svg_-300x209.png 300w, https:\/\/stg-blogs.bmj.com\/adc\/files\/2015\/11\/1024px-Debate_Logo.svg_.png 1024w\" sizes=\"auto, (max-width: 244px) 100vw, 244px\" \/><\/a>It&#8217;s been a &#8216;debate topic&#8217; from a number of conferences, medical student\u00a0societies and online fora.<\/p>\n<p>Should an intervention without\u00a0evidence ever be undertaken?<\/p>\n<p>There&#8217;s a couple of key elements here: one &#8211; the idea that there can be an intervention &#8216;with no\u00a0evidence&#8217;, and two &#8211; that an absence of evidence should be interpreted\u00a0an evidence of absence of effect. Both are straw men.<\/p>\n<p><!--more-->We&#8217;ve covered this ground before. We&#8217;ve battered on about the need of <a href=\"https:\/\/stg-blogs.bmj.com\/adc\/2013\/12\/08\/basics-what-is-evidence-based-medicine\/\">#realEBM to be the combination of best available evidence, viewed through a lens of clinical expertise and decided in conjunction with patients <\/a>to make an appropriate choice. And that &#8216;<a href=\"https:\/\/stg-blogs.bmj.com\/adc\/2015\/09\/29\/evidence-free-yet-evidence-based-guidelines-again\/\">best available&#8217;<\/a> means exactly that &#8211; so\u00a0that for some things there are multiple, well conducted RCTs, for others there is a report that once, someone with a similar condition got better. Sometimes there is even less &#8211; it truly is a never previously done &#8211; but in those cases we should be talking about research, not EBM, shouldn&#8217;t we?\u00a0Beyond that, there&#8217;s a way of thinking about an\u00a0parachute of evidence &#8211; some of it direct, much of it indirect.<\/p>\n<p>Then there&#8217;s the idea that if you don&#8217;t have evidence of something working, it doesn&#8217;t work. \u00a0Hmmmmmm.\u00a0Now there is a difference between &#8220;This ultraviolet pen torch might well cure your glioblastoma multiforme&#8221; and &#8220;Intranasal diamorphine has good analgesic effects, I wonder if intranasal oxycodone might?&#8221;. That&#8217;s a basic issue of functional credibility. But there&#8217;s also just the issue of precision, uncertainty and truth &#8211; <a href=\"https:\/\/stg-blogs.bmj.com\/adc\/2013\/08\/28\/where-does-ebm-go-without-e\/\">I don&#8217;t know is different than I know it&#8217;s not<\/a>.<\/p>\n<p>So. It&#8217;s not a question to debate. It&#8217;s a question to unpick. And reject as fundamentally failing to understand RealEBM<\/p>\n<p>&#8211; Archi<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>It&#8217;s been a &#8216;debate topic&#8217; from a number of conferences, medical student\u00a0societies and online fora. Should an intervention without\u00a0evidence ever be undertaken? There&#8217;s a couple of key elements here: one &#8211; the idea that there can be an intervention &#8216;with no\u00a0evidence&#8217;, and two &#8211; that an absence of evidence should be interpreted\u00a0an evidence of absence [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/stg-blogs.bmj.com\/adc\/2015\/11\/17\/interventions-without-evidence-should-not-be-undertaken-discuss\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[79],"tags":[],"class_list":["post-1197","post","type-post","status-publish","format-standard","hentry","category-archimedes"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/posts\/1197","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/comments?post=1197"}],"version-history":[{"count":0,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/posts\/1197\/revisions"}],"wp:attachment":[{"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/media?parent=1197"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/categories?post=1197"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stg-blogs.bmj.com\/adc\/wp-json\/wp\/v2\/tags?post=1197"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}