{"id":1978,"date":"2011-10-18T04:42:35","date_gmt":"2011-10-18T03:42:35","guid":{"rendered":"http:\/\/stg-blogs.bmj.com\/bjsm\/?p=1978"},"modified":"2011-10-18T20:50:19","modified_gmt":"2011-10-18T19:50:19","slug":"no-magical-therapeutic-benefit-of-prp-in-achilles-tendinopathy-jama-paper-follow-up-and-bjsm-podcast","status":"publish","type":"post","link":"http:\/\/stg-blogs.bmj.com\/bjsm\/2011\/10\/18\/no-magical-therapeutic-benefit-of-prp-in-achilles-tendinopathy-jama-paper-follow-up-and-bjsm-podcast\/","title":{"rendered":"No magical therapeutic benefit of PRP in Achilles tendinopathy &#8212; JAMA paper follow-up and BJSM podcast"},"content":{"rendered":"<p style=\"text-align: center\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-2001 aligncenter\" title=\"untitled\" src=\"https:\/\/stg-blogs.bmj.com\/bjsm\/files\/2011\/10\/PRP-Final-BJSM-cover1.jpg\" alt=\"\" width=\"230\" height=\"309\" \/><\/p>\n<p style=\"text-align: left\">My sense is that the popularity of platelet-rich plasma (PRP) is increasing independent of research in this field. BJSM has covered this with front cover attention:<\/p>\n<ul>\n<li><strong><a href=\"http:\/\/bjsm.bmj.com\/content\/44\/9.toc\" target=\"_blank\">Platelet-rich plasma: Debate. <\/a><\/strong><a href=\"http:\/\/bjsm.bmj.com\/content\/44\/9.toc\" target=\"_blank\">Jul 2010, (44)9<\/a><\/li>\n<li><strong><a href=\"http:\/\/bjsm.bmj.com\/content\/44\/15.toc\" target=\"_blank\">IOC consensus paper on the use of platelet-rich plasma in sports medicine.<\/a><span style=\"font-weight: normal\"><a href=\"http:\/\/bjsm.bmj.com\/content\/44\/15.toc\" target=\"_blank\"> Dec 2010, (44)15<\/a><\/span><\/strong><\/li>\n<\/ul>\n<p>Of most interest to blog readers will be the <a href=\"http:\/\/podcasts.bmj.com\/bjsm\/category\/robert-jan-de-vos\/\" target=\"_blank\">Podcast on PRP with\u00a0Robert Jan de Vos and Adam Weir<\/a>. These authors have arguably the highest quality study testing PRP to date.  We congratulate the Dutch researchers on their quality study design and comprehensive investigations.<\/p>\n<p><strong>Conclusions?<\/strong><\/p>\n<p><strong> <\/strong> &#8211; No clinical benefit in 6 months:<\/p>\n<ul>\n<li><a href=\"http:\/\/jama.ama-assn.org\/content\/303\/2\/144.abstract\" target=\"_blank\">de Vos, R, Weir, A et al. 2010. <\/a><strong><a href=\"http:\/\/jama.ama-assn.org\/content\/303\/2\/144.abstract\" target=\"_blank\">Platelet-Rich Plasma Injection for Chronic Achilles Tendinopathy. <\/a><\/strong><a href=\"http:\/\/jama.ama-assn.org\/content\/303\/2\/144.abstract\" target=\"_blank\">JAMA, 303(2)<\/a><\/li>\n<\/ul>\n<p>&#8211;\u00a0\u00a0No ultrasound evidence of benefit:<\/p>\n<ul>\n<li><a href=\"http:\/\/bjsm.bmj.com\/content\/45\/5\/387.full?sid=55e2a47a-e1db-4787-93ec-779603f0fd9e\" target=\"_blank\">de Vos, R, Weir, A et al. 2010. <\/a><strong><a href=\"http:\/\/bjsm.bmj.com\/content\/45\/5\/387.full?sid=55e2a47a-e1db-4787-93ec-779603f0fd9e\" target=\"_blank\">No effects of PRP on ultrasonographic tendon structure and neovascularisation in chronic midportion Achilles tendinopathy. <\/a><\/strong><a href=\"http:\/\/bjsm.bmj.com\/content\/45\/5\/387.full?sid=55e2a47a-e1db-4787-93ec-779603f0fd9e\" target=\"_blank\">BJSM, Online first November, 2010<\/a><\/li>\n<\/ul>\n<p>&#8211; and now no benefit at 12 months:<\/p>\n<ul>\n<li><a href=\"http:\/\/ajs.sagepub.com\/content\/early\/2011\/05\/20\/0363546511404877\" target=\"_blank\"> de Jonge, S, de Vos, R., Weir, A et al. 2011. <\/a><strong><a href=\"http:\/\/ajs.sagepub.com\/content\/early\/2011\/05\/20\/0363546511404877\" target=\"_blank\">One-Year Follow-up of Platelet-Rich Plasma Treatment in Chronic Achilles Tendinopathy: A Double-Blind Randomized Placebo-Controlled Trial. <\/a><cite><abbr title=\"The American Journal of Sports Medicine\"><span style=\"font-style: normal\"><span style=\"font-weight: normal\"><a href=\"http:\/\/ajs.sagepub.com\/content\/early\/2011\/05\/20\/0363546511404877\" target=\"_blank\">AJSM<\/a>. <\/span><\/span><\/abbr><span style=\"font-style: normal\"><span style=\"font-weight: normal\"><a href=\"http:\/\/ajs.sagepub.com\/content\/early\/2011\/05\/20\/0363546511404877\" target=\"_blank\">August \u00a039.<\/a><\/span><\/span><\/cite><\/strong><\/li>\n<\/ul>\n<p>No benefit at 12 months is not a surprise given previous findings. The proposed mechanism for PRP therapy is accelerated early healing. Nevertheless, these data are important as some evangelical PRP providers may be tempted to discount the 6-month results and argue for a &#8216;delayed benefit&#8217;. This is not the last word on PRP and BJSM Associate Editor Kim Harmon (see:\u00a0<strong><a href=\"http:\/\/bjsm.bmj.com\/content\/44\/16\/1135.full?sid=0f982707-136a-4a5a-a9c4-dd8437fb269a\" target=\"_blank\">Musculoskeletal ultrasound: taking sports medicine to the next level<\/a><\/strong>)\u00a0has pointed out reasons for this series of Dutch studies having &#8216;no effect&#8217;.  BJSM is one of the leading venues for rational debate on PRP and we look forward to adding to your knowledge about the clinical utility of this &#8216;hot&#8217; therapy that is gaining clinical popularity. Time for a quality randomized trial of PRP versus the Alfredson program for Achilles tendinopathy?<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>My sense is that the popularity of platelet-rich plasma (PRP) is increasing independent of research in this field. BJSM has covered this with front cover attention: Platelet-rich plasma: Debate. Jul 2010, (44)9 IOC consensus paper on the use of platelet-rich plasma in sports medicine. Dec 2010, (44)15 Of most interest to blog readers will be [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"http:\/\/stg-blogs.bmj.com\/bjsm\/2011\/10\/18\/no-magical-therapeutic-benefit-of-prp-in-achilles-tendinopathy-jama-paper-follow-up-and-bjsm-podcast\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1,202,317],"tags":[1859],"class_list":["post-1978","post","type-post","status-publish","format-standard","hentry","category-uncategorized","category-podcast","category-research","tag-platelet-rich-plasma"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/stg-blogs.bmj.com\/bjsm\/wp-json\/wp\/v2\/posts\/1978","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/stg-blogs.bmj.com\/bjsm\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/stg-blogs.bmj.com\/bjsm\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/stg-blogs.bmj.com\/bjsm\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/stg-blogs.bmj.com\/bjsm\/wp-json\/wp\/v2\/comments?post=1978"}],"version-history":[{"count":0,"href":"http:\/\/stg-blogs.bmj.com\/bjsm\/wp-json\/wp\/v2\/posts\/1978\/revisions"}],"wp:attachment":[{"href":"http:\/\/stg-blogs.bmj.com\/bjsm\/wp-json\/wp\/v2\/media?parent=1978"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/stg-blogs.bmj.com\/bjsm\/wp-json\/wp\/v2\/categories?post=1978"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/stg-blogs.bmj.com\/bjsm\/wp-json\/wp\/v2\/tags?post=1978"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}